Does Accutane Make Psoriasis Worse?
Psoriasis is a chronic skin condition that affects millions of people worldwide. It is characterized by red, scaly patches on the skin that can be itchy and painful. While there are various treatments available for psoriasis, one of the most controversial is Accutane, a powerful medication used to treat severe acne. The question on many minds is: does Accutane make psoriasis worse?
Accutane, also known as isotretinoin, is a derivative of vitamin A that works by reducing the production of sebum, the oil that can clog pores and lead to acne. It is often prescribed for patients with severe acne that does not respond to other treatments. However, Accutane has been linked to a range of side effects, including skin dryness, nosebleeds, and even depression.
One of the most concerning side effects of Accutane is its potential impact on psoriasis. While there is no definitive answer to whether Accutane makes psoriasis worse, some evidence suggests that it can exacerbate the condition. A study published in the Journal of the American Academy of Dermatology found that patients with both psoriasis and severe acne who were treated with Accutane experienced a worsening of their psoriasis symptoms.
The study involved 23 patients with both conditions who were treated with Accutane. Researchers found that 43% of the patients experienced a worsening of their psoriasis, with symptoms such as redness, scaling, and itching becoming more severe. Additionally, some patients reported a delay in the response to Accutane, with their acne clearing up more slowly than expected.
While the study provides some evidence that Accutane can worsen psoriasis, it is important to note that not all patients will experience this side effect. In fact, some patients may find that Accutane helps to improve their psoriasis symptoms. However, it is crucial for patients with both psoriasis and severe acne to discuss the potential risks and benefits of Accutane with their dermatologist before starting treatment.
Dermatologists recommend that patients with psoriasis who are considering Accutane treatment closely monitor their skin for any signs of worsening symptoms. If psoriasis symptoms do worsen, the patient should contact their dermatologist immediately to discuss alternative treatment options.
In conclusion, while there is evidence to suggest that Accutane can make psoriasis worse, the impact of the medication on individual patients can vary. It is essential for patients with both psoriasis and severe acne to consult with their dermatologist to determine the best treatment plan for their specific condition. By carefully weighing the potential risks and benefits, patients can make an informed decision about whether Accutane is the right treatment for them.
